Background Information Of Portal Hypertension

  • Portal hypertension is hypertension (high blood pressure) in the hepatic portal system – made up of the portal vein and its branches, that drain from most of the intestine to the liver. Portal hypertension is defined as a hepatic venous pressure gradient. Cirrhosis (a form of chronic liver failure) is the most common cause of portal hypertension; other, less frequent causes are therefore grouped as non-cirrhotic portal hypertension. When it becomes severe enough to cause symptoms or complications, treatment may be given to decrease portal hypertension itself or to manage its complications.    —— Wikipedia

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    Cirrhosis is an end liver disease with very high incidence in China.

    Portal hypertension is the most common complication of cirrhosis. Depending on the patient's different portal pressures, patients can be risk stratified to accurately guide subsequent treatment decision and clinical management.

Portal Hypertension Measurement

  • Conventional portal hypertension measurement

    The hepatic vein wedge pressure and free pressure were measured by jugular vein cannulation, and the difference between the two was obtained as hepatic venous pressure gradient, which reflected the portal vein pressure.

    Invasive procedure

    Costly

  • PortoGuard

    Based on CT imaging and radiomics technology, the massive features of liver and spleen were extracted and analyzed, and patients were classified according to different portal hypertension risks.

    Non-invasive procedure

    Affordable.

    Cost about1/10 of the conventional method.

Publications

 

Diagnostic Accuracy of Radiomics-based Hepatic Venous Pressure Gradient for Clinically Significant Portal Hypertension in Cirrhosis,AASLD LiverLearning®.
Qi X. Oct 20, 2017; 194028.

 

Wu, Qijing, et al. "Report of novel approaches for portal hypertension: SNG of the 26 th Conference of Asian Pacific Association for the Study of the Liver."
AME Medical Journal 2.3 (2017).

Exclusive Collaboration

  • We have collaborated with CHESS research group (China Portal High Pressure Diagnostic Research Group) and will continue to apply artificial intelligence in the field of cirrhotic portal hypertension assessment.

  • Non-invasive, Real Time And Accurate Online

    Analysis System For Cirrhotic Portal Hypertension